Importance of Opening During Pickup Women

I want to look at the actual importance of an opening; the
question being: is it the most important part of pick up or maybe
the least?

I usually go with the latter statement but I also accept that in
some situations the "opener" can be more of a major factor than
in other circumstances.

However, I stick by my opinion that it is never beneficial when
one is putting too much energy and emphasis into a fixed a
routine, or getting hung up too much on that killer opener.